Synthesis of a novel chemotype via sequential metal-catalyzed cycloisomerizations

Sequential cycloisomerizations of diynyl o-benzaldehyde substrates to access novel polycyclic cyclopropanes are reported. The reaction sequence involves initial Cu(I)-mediated cycloisomerization/nucleophilic addition to an isochromene followed by diastereoselective Pt(II)-catalyzed enyne cycloisomer...

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Detalles Bibliográficos
Autores principales: Leng, Bo, Chichetti, Stephanie, Su, Shun, Beeler, Aaron B, Porco, John A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2012
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458758/
https://www.ncbi.nlm.nih.gov/pubmed/23019468
http://dx.doi.org/10.3762/bjoc.8.153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458758/
https://www.ncbi.nlm.nih.gov/pubmed/23019468
http://dx.doi.org/10.3762/bjoc.8.153

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