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Intrahepatic Infiltrating NK and CD8 T Cells Cause Liver Cell Death in Different Phases of Dengue Virus Infection

Elevated liver enzyme level is an outstanding feature in patients with dengue. However, the pathogenic mechanism of liver injury has not been clearly demonstrated. In this study, employing a mouse model we aimed to investigate the immunopathogenic mechanism of dengue liver injury. Immunocompetent C5...

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Detalles Bibliográficos
Autores principales: Sung, Jui-Min, Lee, Chien-Kuo, Wu-Hsieh, Betty A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458800/
https://www.ncbi.nlm.nih.gov/pubmed/23050007
http://dx.doi.org/10.1371/journal.pone.0046292