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Intrahepatic Infiltrating NK and CD8 T Cells Cause Liver Cell Death in Different Phases of Dengue Virus Infection
Elevated liver enzyme level is an outstanding feature in patients with dengue. However, the pathogenic mechanism of liver injury has not been clearly demonstrated. In this study, employing a mouse model we aimed to investigate the immunopathogenic mechanism of dengue liver injury. Immunocompetent C5...
Autores principales: | Sung, Jui-Min, Lee, Chien-Kuo, Wu-Hsieh, Betty A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458800/ https://www.ncbi.nlm.nih.gov/pubmed/23050007 http://dx.doi.org/10.1371/journal.pone.0046292 |
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