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Gene-Wide Characterization of Common Quantitative Trait Loci for ABCB1 mRNA Expression in Normal Liver Tissues in the Chinese Population

In order to comprehensively screen genetic variants leading to differential expression of the important human ABCB1 gene in the primary drug-metabolizing organ, ABCB1 mRNA expression levels were measured in 73 normal liver tissue samples from Chinese subjects. A set of Tag SNPs. were genotyped. In a...

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Detalles Bibliográficos
Autores principales: Shou, Weihua, Wang, Dazhi, Zhang, Kaiyue, Wang, Beilan, Wang, Zhimin, Shi, Jinxiu, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458811/
https://www.ncbi.nlm.nih.gov/pubmed/23050008
http://dx.doi.org/10.1371/journal.pone.0046295