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Identification of Anaphase Promoting Complex Substrates in S. cerevisiae

The Anaphase-Promoting Complex/Cyclosome (APC/C) is an essential ubiquitin ligase that targets numerous proteins for proteasome-mediated degradation in mitosis and G1. To gain further insight into cellular pathways controlled by APC/C(Cdh1), we developed two complementary approaches to identify addi...

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Detalles Bibliográficos
Autores principales: Ostapenko, Denis, Burton, Janet L., Solomon, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458821/
https://www.ncbi.nlm.nih.gov/pubmed/23049888
http://dx.doi.org/10.1371/journal.pone.0045895