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Caveolin-1 Deficiency Leads to Increased Susceptibility to Cell Death and Fibrosis in White Adipose Tissue: Characterization of a Lipodystrophic Model

Caveolin-1 (CAV1) is an important regulator of adipose tissue homeostasis. In the present study we examined the impact of CAV1 deficiency on the properties of mouse adipose tissue both in vivo and in explant cultures during conditions of metabolic stress. In CAV1(−/−) mice fasting caused loss of adi...

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Detalles Bibliográficos
Autores principales: Martin, Sally, Fernandez-Rojo, Manuel A., Stanley, Amanda C., Bastiani, Michele, Okano, Satomi, Nixon, Susan J., Thomas, Gethin, Stow, Jennifer L., Parton, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458842/
https://www.ncbi.nlm.nih.gov/pubmed/23049990
http://dx.doi.org/10.1371/journal.pone.0046242