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Caveolin-1 Deficiency Leads to Increased Susceptibility to Cell Death and Fibrosis in White Adipose Tissue: Characterization of a Lipodystrophic Model
Caveolin-1 (CAV1) is an important regulator of adipose tissue homeostasis. In the present study we examined the impact of CAV1 deficiency on the properties of mouse adipose tissue both in vivo and in explant cultures during conditions of metabolic stress. In CAV1(−/−) mice fasting caused loss of adi...
Autores principales: | Martin, Sally, Fernandez-Rojo, Manuel A., Stanley, Amanda C., Bastiani, Michele, Okano, Satomi, Nixon, Susan J., Thomas, Gethin, Stow, Jennifer L., Parton, Robert G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458842/ https://www.ncbi.nlm.nih.gov/pubmed/23049990 http://dx.doi.org/10.1371/journal.pone.0046242 |
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