Co-Factor Binding Confers Substrate Specificity to Xylose Reductase from Debaryomyces hansenii

Binding of substrates into the active site, often through complementarity of shapes and charges, is central to the specificity of an enzyme. In many cases, substrate binding induces conformational changes in the active site, promoting specific interactions between them. In contrast, non-substrates e...

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Detalles Bibliográficos
Autores principales: Biswas, Dipanwita, Pandya, Vaibhav, Singh, Appu Kumar, Mondal, Alok K., Kumaran, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458928/
https://www.ncbi.nlm.nih.gov/pubmed/23049810
http://dx.doi.org/10.1371/journal.pone.0045525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458928/
https://www.ncbi.nlm.nih.gov/pubmed/23049810
http://dx.doi.org/10.1371/journal.pone.0045525

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