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Co-Factor Binding Confers Substrate Specificity to Xylose Reductase from Debaryomyces hansenii
Binding of substrates into the active site, often through complementarity of shapes and charges, is central to the specificity of an enzyme. In many cases, substrate binding induces conformational changes in the active site, promoting specific interactions between them. In contrast, non-substrates e...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458928/ https://www.ncbi.nlm.nih.gov/pubmed/23049810 http://dx.doi.org/10.1371/journal.pone.0045525 |