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Cytoplasmic and Nuclear Anti-Apoptotic Roles of αB-Crystallin in Retinal Pigment Epithelial Cells

In addition to its well-characterized role in the lens, αB-crystallin performs other functions. Methylglyoxal (MGO) can alter the function of the basement membrane of retinal pigment epithelial (RPE) cells. Thus, if MGO is not efficiently detoxified, it can induce adverse reactions in RPE cells. In...

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Detalles Bibliográficos
Autores principales: Jeong, Woo Jin, Rho, Jee Hyun, Yoon, Young Geol, Yoo, Seung Hee, Jeong, Na Young, Ryu, Won Yeol, Ahn, Hee Bae, Park, Woo Chan, Rho, Sae Heun, Yoon, Hee Seong, Choi, Yung Hyun, Yoo, Young Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458930/
https://www.ncbi.nlm.nih.gov/pubmed/23049853
http://dx.doi.org/10.1371/journal.pone.0045754