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Recurrent/moderate hypoglycemia induces hippocampal dendritic injury, microglial activation, and cognitive impairment in diabetic rats
BACKGROUND: Recurrent/moderate (R/M) hypoglycemia is common in type 1 diabetes. Although mild or moderate hypoglycemia is not life-threatening, if recurrent, it may cause cognitive impairment. In the present study, we sought to determine whether R/M hypoglycemia leads to neuronal death, dendritic in...
Autores principales: | Won, Seok Joon, Yoo, Byung Hoon, Kauppinen, Tiina M, Choi, Bo Young, Kim, Jin Hee, Jang, Bong Geom, Lee, Min Woo, Sohn, Min, Liu, Jialing, Swanson, Raymond A, Suh, Sang Won |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458941/ https://www.ncbi.nlm.nih.gov/pubmed/22830525 http://dx.doi.org/10.1186/1742-2094-9-182 |
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