Prolonged and Substantial Discordance in Prevalence of Raltegravir-Resistant HIV-1 in Plasma versus PBMC Samples Revealed by 454 “Deep” Sequencing

The evolution of drug resistance mutations in plasma samples is relatively well-characterized. However, the viral population and diversity in other body compartments such as peripheral blood mononuclear cells (PBMC) remains poorly understood. Previous studies have mostly focused on protease and reve...

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Detalles Bibliográficos
Autores principales: Lee, Guinevere Q., Swenson, Luke C., Poon, Art F. Y., Martin, Jeffrey N., Hatano, Hiroyu, Deeks, Steven G., Harrigan, P. Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458959/
https://www.ncbi.nlm.nih.gov/pubmed/23049972
http://dx.doi.org/10.1371/journal.pone.0046181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458959/
https://www.ncbi.nlm.nih.gov/pubmed/23049972
http://dx.doi.org/10.1371/journal.pone.0046181

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