Prolonged and Substantial Discordance in Prevalence of Raltegravir-Resistant HIV-1 in Plasma versus PBMC Samples Revealed by 454 “Deep” Sequencing

The evolution of drug resistance mutations in plasma samples is relatively well-characterized. However, the viral population and diversity in other body compartments such as peripheral blood mononuclear cells (PBMC) remains poorly understood. Previous studies have mostly focused on protease and reve...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Guinevere Q., Swenson, Luke C., Poon, Art F. Y., Martin, Jeffrey N., Hatano, Hiroyu, Deeks, Steven G., Harrigan, P. Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458959/
https://www.ncbi.nlm.nih.gov/pubmed/23049972
http://dx.doi.org/10.1371/journal.pone.0046181

Ejemplares similares

Ejemplares similares