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Influence of IL17A polymorphisms on the aberrant methylation of DAPK and CDH1 in non-cancerous gastric mucosa

BACKGROUND: CpG island aberrant methylation is shown to be an important mechanism in gene silencing. The important role of IL-17 in inflammatory response to H. pylori colonization has been indicated. We investigated the influence of IL17A polymorphisms, -197 G > A (rs2275913) and *1249 C > T (...

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Detalles Bibliográficos
Autores principales: Arisawa, Tomiyasu, Tahara, Tomomitsu, Tsutsumi, Mikihiro, Shibata, Tomoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458965/
https://www.ncbi.nlm.nih.gov/pubmed/22827846
http://dx.doi.org/10.1186/1471-2350-13-59