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Adenosine A(2B) receptor-mediated leukemia inhibitory factor release from astrocytes protects cortical neurons against excitotoxicity

BACKGROUND: Neuroprotective and neurotrophic properties of leukemia inhibitory factor (LIF) have been widely reported. In the central nervous system (CNS), astrocytes are the major source for LIF, expression of which is enhanced following disturbances leading to neuronal damage. How astrocytic LIF e...

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Detalles Bibliográficos
Autores principales: Moidunny, Shamsudheen, Vinet, Jonathan, Wesseling, Evelyn, Bijzet, Johan, Shieh, Chu-Hsin, van Ijzendoorn, Sven CD, Bezzi, Paola, Boddeke, Hendrikus WGM, Biber, Knut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458985/
https://www.ncbi.nlm.nih.gov/pubmed/22894638
http://dx.doi.org/10.1186/1742-2094-9-198