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Keratinocyte expression of inflammatory mediators plays a crucial role in substance P-induced acute and chronic pain

Tibia fracture in rats followed by cast immobilization leads to nociceptive, trophic, vascular and bone-related changes similar to those seen in Complex Regional Pain Syndrome (CRPS). Substance P (SP) mediated neurogenic inflammation may be responsible for some of the signs of CRPS in humans. We the...

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Detalles Bibliográficos
Autores principales: Wei, Tzuping, Guo, Tian-Zhi, Li, Wen-Wu, Hou, Saiyun, Kingery, Wade S, Clark, John David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458986/
https://www.ncbi.nlm.nih.gov/pubmed/22824437
http://dx.doi.org/10.1186/1742-2094-9-181