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IgG glycan hydrolysis by EndoS inhibits experimental autoimmune encephalomyelitis
Studies in experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis, have shown that B cells markedly influence the course of the disease, although whether their effects are protective or pathological is a matter of debate. EndoS hydrolysis of the IgG glycan has profound...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458989/ https://www.ncbi.nlm.nih.gov/pubmed/22943418 http://dx.doi.org/10.1186/1742-2094-9-209 |