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Cholesteryl ester accumulation and accelerated cholesterol absorption in intestine-specific hormone sensitive lipase-null mice

Hormone sensitive lipase (HSL) regulates the hydrolysis of acylglycerols and cholesteryl esters (CE) in various cells and organs, including enterocytes of the small intestine. The physiological role of this enzyme in enterocytes, however, stayed elusive. In the present study we generated mice lackin...

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Detalles Bibliográficos
Autores principales: Obrowsky, Sascha, Chandak, Prakash G., Patankar, Jay V., Pfeifer, Thomas, Povoden, Silvia, Schreiber, Renate, Haemmerle, Guenter, Levak-Frank, Sanja, Kratky, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459056/
https://www.ncbi.nlm.nih.gov/pubmed/22842588
http://dx.doi.org/10.1016/j.bbalip.2012.07.013