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MCP-1-Induced Histamine Release from Mast Cells Is Associated with Development of Interstitial Cystitis/Bladder Pain Syndrome in Rat Models

Objective. Interstitial cystitis/bladder pain syndrome (IC/BPS) is characterized by overexpression of monocyte chemoattractant protein-1 (MCP-1) in bladder tissues and induction of mast cell (MC) degranulation. This study was undertaken to explore the mechanism of action of MCP-1 in the development...

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Detalles Bibliográficos
Autores principales: Lv, Jianwei, Huang, Yiran, Zhu, Shiguo, Yang, Ganggang, Zhang, Yujian, Leng, Jing, Bo, Juanjie, Liu, Dongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459284/
https://www.ncbi.nlm.nih.gov/pubmed/23049171
http://dx.doi.org/10.1155/2012/358184