Fractional Proliferation: A method to deconvolve cell population dynamics from single-cell data

We present an integrated method that exploits extended time-lapse automated imaging to quantify dynamics of cell proliferation. Cell counts are fit with a Quiescence-Growth model that estimates rates of cell division, entry into quiescence and death. The model is constrained with rates extracted exp...

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Detalles Bibliográficos
Autores principales: Tyson, Darren R., Garbett, Shawn P., Frick, Peter L., Quaranta, Vito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459330/
https://www.ncbi.nlm.nih.gov/pubmed/22886092
http://dx.doi.org/10.1038/nmeth.2138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459330/
https://www.ncbi.nlm.nih.gov/pubmed/22886092
http://dx.doi.org/10.1038/nmeth.2138

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