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Fractional Proliferation: A method to deconvolve cell population dynamics from single-cell data
We present an integrated method that exploits extended time-lapse automated imaging to quantify dynamics of cell proliferation. Cell counts are fit with a Quiescence-Growth model that estimates rates of cell division, entry into quiescence and death. The model is constrained with rates extracted exp...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459330/ https://www.ncbi.nlm.nih.gov/pubmed/22886092 http://dx.doi.org/10.1038/nmeth.2138 |