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Are mouse models of asthma appropriate for investigating the pathogenesis of airway hyper-responsiveness?
Whether mouse models of chronic asthma can be used to investigate the relationship between airway inflammation/remodeling and airway hyper-responsiveness (AHR) is a vexed question. It raises issues about the extent to which such models replicate key features of the human disease. Here, we review som...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459343/ https://www.ncbi.nlm.nih.gov/pubmed/23060800 http://dx.doi.org/10.3389/fphys.2012.00312 |