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Stable silencing of β-lactoglobulin (BLG) gene by lentivirus-mediated RNAi in goat fetal fibroblasts

β-lactoglobulin (BLG), a dominant allergen in goat milk, is difficult to remove by traditional biochemical methods. Its elimination from goat milk by genetic modification therefore poses a major challenge for modern goat breeders. A shRNA targeting BLG mRNA with high interference efficiency was iden...

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Detalles Bibliográficos
Autores principales: Zhang, Shumin, Xiong, Kai, Xie, Zhourui, Nan, Wenting, Liu, Honglin, Chen, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459420/
https://www.ncbi.nlm.nih.gov/pubmed/23055809
http://dx.doi.org/10.1590/S1415-47572012005000042