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Induction and molecular signature of pathogenic T(H)17 cells

Interleukin 17 (IL-17)-producing T(H)17 cells are often present at the sites of tissue inflammation in autoimmune diseases, which has lead to the conclusion that T(H)17 are main drivers of autoimmune tissue injury. However, not all T(H)17 cells are pathogenic, in fact T(H)17 generated with TGF-β1 an...

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Detalles Bibliográficos
Autores principales: Lee, Youjin, Awasthi, Amit, Yosef, Nir, Quintana, Francisco J., Xiao, Sheng, Peters, Anneli, Wu, Chuan, Kleinewietfeld, Markus, Kunder, Sharon, Hafler, David, Sobel, Raymond A., Regev, Aviv, Kuchroo, Vijay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459594/
https://www.ncbi.nlm.nih.gov/pubmed/22961052
http://dx.doi.org/10.1038/ni.2416