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Induction and molecular signature of pathogenic T(H)17 cells
Interleukin 17 (IL-17)-producing T(H)17 cells are often present at the sites of tissue inflammation in autoimmune diseases, which has lead to the conclusion that T(H)17 are main drivers of autoimmune tissue injury. However, not all T(H)17 cells are pathogenic, in fact T(H)17 generated with TGF-β1 an...
Autores principales: | Lee, Youjin, Awasthi, Amit, Yosef, Nir, Quintana, Francisco J., Xiao, Sheng, Peters, Anneli, Wu, Chuan, Kleinewietfeld, Markus, Kunder, Sharon, Hafler, David, Sobel, Raymond A., Regev, Aviv, Kuchroo, Vijay K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459594/ https://www.ncbi.nlm.nih.gov/pubmed/22961052 http://dx.doi.org/10.1038/ni.2416 |
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