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Cell-penetrating superoxide dismutase attenuates oxidative stress-induced senescence by regulating the p53-p21(Cip1) pathway and restores osteoblastic differentiation in human dental pulp stem cells

BACKGROUND: Human dental pulp stem cells (DPSCs) have potential applications in tissue regeneration because of their convenient cell harvesting procedures and multipotent capacity. However, the tissue regenerative potential of DPSCs is known to be negatively regulated by aging in long-term culture a...

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Detalles Bibliográficos
Autores principales: Choi, Yoon Jung, Lee, Jue Yeon, Chung, Chong Pyoung, Park, Yoon Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459692/
https://www.ncbi.nlm.nih.gov/pubmed/23049256
http://dx.doi.org/10.2147/IJN.S31723