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Significance of decoy receptor 3 (Dcr3) and external-signal regulated kinase 1/2 (Erk1/2) in gastric cancer

BACKGROUND: Decoy receptor 3 (DcR3), a member of the tumor necrosis factor receptor (TNFR) superfamily, is associated with anti-tumor immunity suppression. It is highly expressed in many tumors, and its expression can be regulated by the MAPK/MEK/ERK signaling pathway. The MAPK/MEK/ERK pathway has b...

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Detalles Bibliográficos
Autores principales: Yang, Donghai, Fan, Xin, Yin, Ping, Wen, Qiang, Yan, Feng, Yuan, Sibo, Liu, Bin, Zhuang, Guohong, Liu, Zhongchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459731/
https://www.ncbi.nlm.nih.gov/pubmed/22672288
http://dx.doi.org/10.1186/1471-2172-13-28