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Methylenetetrahydrofolate Reductase Polymorphisms and Risk of Acute Lymphoblastic Leukemia-Evidence from an updated meta-analysis including 35 studies

BACKGROUND: 5,10-methylenetetrahydrofolate reductase (MTHFR) variants, C677T and A1298C, have been reported to be associated with decreased risk of acute lymphoblastic leukemia (ALL). However, results derived from individually underpowered studies are conflicting. We carried out an updated meta-anal...

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Detalles Bibliográficos
Autores principales: Wang, Haigang, Wang, Jiali, Zhao, Lixia, Liu, Xinchun, Mi, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459788/
https://www.ncbi.nlm.nih.gov/pubmed/22943282
http://dx.doi.org/10.1186/1471-2350-13-77