Computational identification and experimental validation of microRNAs binding to the Alzheimer-related gene ADAM10

BACKGROUND: MicroRNAs (miRNAs) are post-transcriptional regulators involved in numerous biological processes including the pathogenesis of Alzheimer’s disease (AD). A key gene of AD, ADAM10, controls the proteolytic processing of APP and the formation of the amyloid plaques and is known to be regula...

Descripción completa

Detalles Bibliográficos
Autores principales: Augustin, Regina, Endres, Kristina, Reinhardt, Sven, Kuhn, Peer-Hendrik, Lichtenthaler, Stefan F, Hansen, Jens, Wurst, Wolfgang, Trümbach, Dietrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459808/
https://www.ncbi.nlm.nih.gov/pubmed/22594617
http://dx.doi.org/10.1186/1471-2350-13-35

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459808/
https://www.ncbi.nlm.nih.gov/pubmed/22594617
http://dx.doi.org/10.1186/1471-2350-13-35

Ejemplares similares