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Computational identification and experimental validation of microRNAs binding to the Alzheimer-related gene ADAM10

BACKGROUND: MicroRNAs (miRNAs) are post-transcriptional regulators involved in numerous biological processes including the pathogenesis of Alzheimer’s disease (AD). A key gene of AD, ADAM10, controls the proteolytic processing of APP and the formation of the amyloid plaques and is known to be regula...

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Detalles Bibliográficos
Autores principales:	Augustin, Regina, Endres, Kristina, Reinhardt, Sven, Kuhn, Peer-Hendrik, Lichtenthaler, Stefan F, Hansen, Jens, Wurst, Wolfgang, Trümbach, Dietrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459808/ https://www.ncbi.nlm.nih.gov/pubmed/22594617 http://dx.doi.org/10.1186/1471-2350-13-35

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