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Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett’s esophagus
Barrett’s Esophagus is an increasingly common disease that is strongly associated with reflux of stomach acid and usually a hiatus hernia. Barrett’s Esophagus strongly predisposes to esophageal adenocarcinoma (EAC), a tumour with a very poor prognosis. We have undertaken the first genome-wide associ...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459818/ https://www.ncbi.nlm.nih.gov/pubmed/22961001 http://dx.doi.org/10.1038/ng.2408 |