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A New Slow Releasing, H(2)S Generating Compound, GYY4137 Relaxes Spontaneous and Oxytocin-Stimulated Contractions of Human and Rat Pregnant Myometrium

Better tocolytics are required to help prevent preterm labour. The gaseotransmitter Hydrogen sulphide (H(2)S) has been shown to reduce myometrial contractility and thus is of potential interest. However previous studies used NaHS, which is toxic and releases H(2)S as a non-physiological bolus and th...

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Detalles Bibliográficos
Autores principales: Robinson, Hayley, Wray, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459845/
https://www.ncbi.nlm.nih.gov/pubmed/23029460
http://dx.doi.org/10.1371/journal.pone.0046278