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Alternative splicing results in RET isoforms with distinct trafficking properties

RET encodes a receptor tyrosine kinase that is essential for spermatogenesis, development of the sensory, sympathetic, parasympathetic, and enteric nervous systems and the kidneys, as well as for maintenance of adult midbrain dopaminergic neurons. RET is alternatively spliced to encode multiple isof...

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Detalles Bibliográficos
Autores principales: Richardson, Douglas S., Rodrigues, David M., Hyndman, Brandy D., Crupi, Mathieu J. F., Nicolescu, Adrian C., Mulligan, Lois M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459860/
https://www.ncbi.nlm.nih.gov/pubmed/22875993
http://dx.doi.org/10.1091/mbc.E12-02-0114