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Combined computational and experimental analysis reveals mitogen-activated protein kinase–mediated feedback phosphorylation as a mechanism for signaling specificity

Different environmental stimuli often use the same set of signaling proteins to achieve very different physiological outcomes. The mating and invasive growth pathways in yeast each employ a mitogen-activated protein (MAP) kinase cascade that includes Ste20, Ste11, and Ste7. Whereas proper mating req...

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Detalles Bibliográficos
Autores principales: Hao, Nan, Yildirim, Necmettin, Nagiec, Michal J., Parnell, Stephen C., Errede, Beverly, Dohlman, Henrik G., Elston, Timothy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459865/
https://www.ncbi.nlm.nih.gov/pubmed/22875986
http://dx.doi.org/10.1091/mbc.E12-04-0333