Enhancing the Prioritization of Disease-Causing Genes through Tissue Specific Protein Interaction Networks

The prioritization of candidate disease-causing genes is a fundamental challenge in the post-genomic era. Current state of the art methods exploit a protein-protein interaction (PPI) network for this task. They are based on the observation that genes causing phenotypically-similar diseases tend to l...

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Detalles Bibliográficos
Autores principales: Magger, Oded, Waldman, Yedael Y., Ruppin, Eytan, Sharan, Roded
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459874/
https://www.ncbi.nlm.nih.gov/pubmed/23028288
http://dx.doi.org/10.1371/journal.pcbi.1002690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459874/
https://www.ncbi.nlm.nih.gov/pubmed/23028288
http://dx.doi.org/10.1371/journal.pcbi.1002690

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