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Paired-End Sequencing of Long-Range DNA Fragments for De Novo Assembly of Large, Complex Mammalian Genomes by Direct Intra-Molecule Ligation

BACKGROUND: The relatively short read lengths from next generation sequencing (NGS) technologies still pose a challenge for de novo assembly of complex mammal genomes. One important solution is to use paired-end (PE) sequence information experimentally obtained from long-range DNA fragments (>1 k...

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Detalles Bibliográficos
Autores principales: Asan, Geng, Chunyu, Chen, Yan, Wu, Kui, Cai, Qingle, Wang, Yu, Lang, Yongshan, Cao, Hongzhi, Yang, Huangming, Wang, Jian, Zhang, Xiuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459883/
https://www.ncbi.nlm.nih.gov/pubmed/23029438
http://dx.doi.org/10.1371/journal.pone.0046211