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Tissue-Specific Functional Networks for Prioritizing Phenotype and Disease Genes

Integrated analyses of functional genomics data have enormous potential for identifying phenotype-associated genes. Tissue-specificity is an important aspect of many genetic diseases, reflecting the potentially different roles of proteins and pathways in diverse cell lineages. Accounting for tissue...

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Detalles Bibliográficos
Autores principales: Guan, Yuanfang, Gorenshteyn, Dmitriy, Burmeister, Margit, Wong, Aaron K., Schimenti, John C., Handel, Mary Ann, Bult, Carol J., Hibbs, Matthew A., Troyanskaya, Olga G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459891/
https://www.ncbi.nlm.nih.gov/pubmed/23028291
http://dx.doi.org/10.1371/journal.pcbi.1002694