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Denatured G-Protein Coupled Receptors as Immunogens to Generate Highly Specific Antibodies
G-protein coupled receptors (GPCRs) play a major role in a number of physiological and pathological processes. Thus, GPCRs have become the most frequent targets for development of new therapeutic drugs. In this context, the availability of highly specific antibodies may be decisive to obtain reliabl...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459905/ https://www.ncbi.nlm.nih.gov/pubmed/23029489 http://dx.doi.org/10.1371/journal.pone.0046348 |