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Denatured G-Protein Coupled Receptors as Immunogens to Generate Highly Specific Antibodies

G-protein coupled receptors (GPCRs) play a major role in a number of physiological and pathological processes. Thus, GPCRs have become the most frequent targets for development of new therapeutic drugs. In this context, the availability of highly specific antibodies may be decisive to obtain reliabl...

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Detalles Bibliográficos
Autores principales: Talmont, Franck, Moulédous, Lionel, Boué, Jérôme, Mollereau, Catherine, Dietrich, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459905/
https://www.ncbi.nlm.nih.gov/pubmed/23029489
http://dx.doi.org/10.1371/journal.pone.0046348