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Regeneration of Stereocilia of Hair Cells by Forced Atoh1 Expression in the Adult Mammalian Cochlea

The hallmark of mechanosensory hair cells is the stereocilia, where mechanical stimuli are converted into electrical signals. These delicate stereocilia are susceptible to acoustic trauma and ototoxic drugs. While hair cells in lower vertebrates and the mammalian vestibular system can spontaneously...

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Detalles Bibliográficos
Autores principales: Yang, Shi-Ming, Chen, Wei, Guo, Wei-Wei, Jia, Shuping, Sun, Jian-He, Liu, Hui-Zhan, Young, Wie-Yen, He, David Z. Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459923/
https://www.ncbi.nlm.nih.gov/pubmed/23029493
http://dx.doi.org/10.1371/journal.pone.0046355