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Automated High-Throughput RNAi Screening in Human Cells Combined with Reporter mRNA Transfection to Identify Novel Regulators of Translation

Proteins that promote angiogenesis, such as vascular endothelial growth factor (VEGF), are major targets for cancer therapy. Accordingly, proteins that specifically activate expression of factors like VEGF are potential alternative therapeutic targets and may help to combat evasive resistance to ang...

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Detalles Bibliográficos
Autores principales: Casanova, Claudia M., Sehr, Peter, Putzker, Kerstin, Hentze, Matthias W., Neumann, Beate, Duncan, Kent E., Thoma, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459937/
https://www.ncbi.nlm.nih.gov/pubmed/23029333
http://dx.doi.org/10.1371/journal.pone.0045943