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Functional Characterisation of the WW Minimal Domain for Delivering Therapeutic Proteins by Adenovirus Dodecahedron

Protein transduction offers a great therapeutic potential by efficient delivery of biologically active cargo into cells. The Adenovirus Dd (Dodecahedron) has recently been shown to deliver proteins fused to the tandem WW(2-3-4) structural domains from the E3 ubiquitin ligase Nedd4. In this study, we...

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Detalles Bibliográficos
Autores principales: Villegas-Méndez, Ana, Fender, Pascal, Garin, Marina I., Rothe, Romy, Liguori, Lavinia, Marques, Bruno, Lenormand, Jean-Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459938/
https://www.ncbi.nlm.nih.gov/pubmed/23028993
http://dx.doi.org/10.1371/journal.pone.0045416