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Limited Evidence for Parent-of-Origin Effects in Inflammatory Bowel Disease Associated Loci
BACKGROUND: Genome-wide association studies of two main forms of inflammatory bowel diseases (IBD), Crohn’s disease (CD) and ulcerative colitis (UC), have identified 99 susceptibility loci, but these explain only ∼23% of the genetic risk. Part of the ‘hidden heritability’ could be in transmissible g...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459955/ https://www.ncbi.nlm.nih.gov/pubmed/23028907 http://dx.doi.org/10.1371/journal.pone.0045287 |