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Glycyrrhetic Acid Synergistically Enhances β(2)-Adrenergic Receptor-Gs Signaling by Changing the Location of Gαs in Lipid Rafts

Glycyrrhetic acid (GA) exerts synergistic anti-asthmatic effects via a β(2)-adrenergic receptor (β(2)AR)-mediated pathway. Cholesterol is an important component of the structure and function of lipid rafts, which play critical roles in the β(2)AR-Gs-adenylate cyclase (AC)-mediated signaling pathway....

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Detalles Bibliográficos
Autores principales:	Shi, Qian, Hou, Yuanyuan, Hou, Jie, Pan, Penwei, Liu, Ze, Jiang, Min, Gao, Jie, Bai, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459958/ https://www.ncbi.nlm.nih.gov/pubmed/23028680 http://dx.doi.org/10.1371/journal.pone.0044921

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