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Latexin Is Down-Regulated in Hematopoietic Malignancies and Restoration of Expression Inhibits Lymphoma Growth

Latexin is a negative regulator of hematopoietic stem cell number in mice. Its dysregulated expression in other tumors led us to hypothesize that latexin may have tumor suppressor properties in hematological malignancies. We found that latexin was down-regulated in a variety of leukemia and lymphoma...

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Detalles Bibliográficos
Autores principales: Liu, Yi, Howard, Dianna, Rector, Kyle, Swiderski, Carol, Brandon, Jason, Schook, Lawrence, Mehta, Jayesh, Bryson, J. Scott, Bondada, Subbarao, Liang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459965/
https://www.ncbi.nlm.nih.gov/pubmed/23028717
http://dx.doi.org/10.1371/journal.pone.0044979