Cargando…

Proteome-Wide Analysis of Disease-Associated SNPs That Show Allele-Specific Transcription Factor Binding

A causative role for single nucleotide polymorphisms (SNPs) in many genetic disorders has become evident through numerous genome-wide association studies. However, identification of these common causal variants and the molecular mechanisms underlying these associations remains a major challenge. Dif...

Descripción completa

Detalles Bibliográficos
Autores principales: Butter, Falk, Davison, Lucy, Viturawong, Tar, Scheibe, Marion, Vermeulen, Michiel, Todd, John A., Mann, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459973/
https://www.ncbi.nlm.nih.gov/pubmed/23028375
http://dx.doi.org/10.1371/journal.pgen.1002982