Cargando…

Complex Chromosomal Rearrangements Mediated by Break-Induced Replication Involve Structure-Selective Endonucleases

DNA double-strand break (DSB) repair occurring in repeated DNA sequences often leads to the generation of chromosomal rearrangements. Homologous recombination normally ensures a faithful repair of DSBs through a mechanism that transfers the genetic information of an intact donor template to the brok...

Descripción completa

Detalles Bibliográficos
Autores principales: Pardo, Benjamin, Aguilera, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459980/
https://www.ncbi.nlm.nih.gov/pubmed/23071463
http://dx.doi.org/10.1371/journal.pgen.1002979