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TIP30 loss enhances cytoplasmic and nuclear EGFR signaling and promotes lung adenocarcinogenesis in mice

Lung adenocarcinoma, the most common type of human non-small cell lung cancer (NSCLC), frequently overexpresses EGFR. However, the mechanisms underlying EGFR overexpression are not completely understood. Recent studies have identified that decreased expression of TIP30 is associated with the metasta...

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Detalles Bibliográficos
Autores principales: Li, Aimin, Zhang, Chengliang, Gao, Shenglan, Chen, Fengsheng, Yang, Chengfen, Luo, Rongcheng, Xiao, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460142/
https://www.ncbi.nlm.nih.gov/pubmed/22733137
http://dx.doi.org/10.1038/onc.2012.253