Copy number variation leads to considerable diversity for B but not A haplotypes of the human KIR genes encoding NK cell receptors

The KIR complex appears to be evolving rapidly in humans, and more than 50 different haplotypes have been described, ranging from four to 14 KIR loci. Previously it has been suggested that most KIR haplotypes consist of framework genes, present in all individuals, which bracket a variable number of...

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Detalles Bibliográficos
Autores principales: Jiang, Wei, Johnson, Chris, Jayaraman, Jyothi, Simecek, Nikol, Noble, Janelle, Moffatt, Miriam F., Cookson, William O., Trowsdale, John, Traherne, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460180/
https://www.ncbi.nlm.nih.gov/pubmed/22948769
http://dx.doi.org/10.1101/gr.137976.112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460180/
https://www.ncbi.nlm.nih.gov/pubmed/22948769
http://dx.doi.org/10.1101/gr.137976.112

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