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Conservation of replication timing reveals global and local regulation of replication origin activity

DNA replication initiates from defined locations called replication origins; some origins are highly active, whereas others are dormant and rarely used. Origins also differ in their activation time, resulting in particular genomic regions replicating at characteristic times and in a defined temporal...

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Detalles Bibliográficos
Autores principales: Müller, Carolin A., Nieduszynski, Conrad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460190/
https://www.ncbi.nlm.nih.gov/pubmed/22767388
http://dx.doi.org/10.1101/gr.139477.112