Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer

Loss of heterozygosity (LOH) and copy number alteration (CNA) feature prominently in the somatic genomic landscape of tumors. As such, karyotypic aberrations in cancer genomes have been studied extensively to discover novel oncogenes and tumor-suppressor genes. Advances in sequencing technology have...

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Detalles Bibliográficos
Autores principales: Ha, Gavin, Roth, Andrew, Lai, Daniel, Bashashati, Ali, Ding, Jiarui, Goya, Rodrigo, Giuliany, Ryan, Rosner, Jamie, Oloumi, Arusha, Shumansky, Karey, Chin, Suet-Feung, Turashvili, Gulisa, Hirst, Martin, Caldas, Carlos, Marra, Marco A., Aparicio, Samuel, Shah, Sohrab P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460194/
https://www.ncbi.nlm.nih.gov/pubmed/22637570
http://dx.doi.org/10.1101/gr.137570.112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460194/
https://www.ncbi.nlm.nih.gov/pubmed/22637570
http://dx.doi.org/10.1101/gr.137570.112

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